منابع مشابه
Genetics of the Dombrock blood group system.
In April I965, anti-Doa, an antibody defining a 'new' red cell antigen, was reported (Swanson, Polesky, Tippett, and Sanger, I965). The present paper records the results of tests with anti-Doa on samples received in this unit from October I964 until April I966. Anti-Doa reacts best by the antiglobulin test on papainized cells, but only a minority of otherwise good antiglobulin sera are suitable...
متن کاملComplexities of the Dombrock blood group system revealed.
The Do(a) antigen was discovered after I began my career in immunohematology and I have been fortunate to be involved in several fascinating discoveries in the Dombrock blood group system. The Do(a) antigen and its antithetical antigen, Do(b), have a prevalence that makes them useful as genetic markers. The paucity of reliable anti-Do(a) and anti-Do(b) has prevented this potential from being re...
متن کاملThe Dombrock system: linkage relations with other blood group loci.
The recognition of the blood group system called Dombrock was reported in 1965 by Swanson and her colleagues. In 1967 Tippett gave an account of the genetics of the system which included an analysis of the linkage relations of the Do locus to other blood group loci, based on families tested in the MRC Blood Group Unit up to April 1966. The present account brings the linkage analysis up to the e...
متن کاملThe Duffy blood group system: a review.
Duffy was the first blood group mapped to an autosome (chromosome 1) using cytogenetic studies. Duffy antigens are located on a glycoprotein that can be found on erythrocytes and other cells throughout the body. Fy(a) and Fy(b) are products of their respective alleles (FY*A, FY*B). Fy(x) characterized by weak Fy(b) expression, is a result of an additional mutation in FY*B. The Fy(a-b-) phenotyp...
متن کاملThe Rh blood group system: a review
The Rh blood group system is one of the most polymorphic and immunogenic systems known in humans. In the past decade, intense investigation has yielded considerable knowledge of the molecular background of this system. The genes encoding 2 distinct Rh proteins that carry C or c together with either E or e antigens, and the D antigen, have been cloned, and the molecular bases of many of the anti...
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ژورنال
عنوان ژورنال: Immunohematology
سال: 2020
ISSN: 0894-203X,1930-3955
DOI: 10.21307/immunohematology-2019-206